T-type amino acid transporter TAT1 (Slc16a10) is essential for extracellular aromatic amino acid homeostasis control
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چکیده
منابع مشابه
T-type amino acid transporter TAT1 (Slc16a10) is essential for extracellular aromatic amino acid homeostasis control.
The uniporter TAT1 (Slc16a10) mediates the facilitated diffusion of aromatic amino acids (AAAs) across basolateral membranes of kidney, small intestine and liver epithelial cells, and across the plasma membrane of non-epithelial cells like skeletal myocytes. Its role for body AA homeostasis has now been investigated using newly generated TAT1 (Slc16a10) defective mice (tat1(-/-)). These mice gr...
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TAT1 (T-type amino acid transporter 1), also known as SLC16A10 (solute carrier family 16, member 10), aromatic amino acid transporter 1, MCT10 (mono carboxylate transporter 10) or PRO0813, is a 515 amino acid protein that belongs to the monocarboxylate porter family. It is a uniporter, which is a Na+-independent transporter of aromatic amino acids (AAA) such as tryptophan, tyrosine, and phenyla...
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ژورنال
عنوان ژورنال: The Journal of Physiology
سال: 2012
ISSN: 0022-3751
DOI: 10.1113/jphysiol.2012.239574